BDBM50377384 AZUMAMIDE C

SMILES CC(C)[C@H]1NC(=O)[C@@H](C)[C@@H](CC=CCCC(O)=O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](C)NC1=O

InChI Key InChIKey=QKNOLJBQLJGNKI-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50377384   

TargetHistone deacetylase 4(Human)
Waseda University

Curated by ChEMBL
LigandPNGBDBM50377384(AZUMAMIDE C)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Waseda University

Curated by ChEMBL
LigandPNGBDBM50377384(AZUMAMIDE C)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Waseda University

Curated by ChEMBL
LigandPNGBDBM50377384(AZUMAMIDE C)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of human HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNuclear receptor corepressor 1(Human)
Technical University of Denmark

Curated by ChEMBL
LigandPNGBDBM50377384(AZUMAMIDE C)
Affinity DataKi:  14nMAssay Description:Inhibition of GST-tagged recombinant human HDAC3/NcoR1 enzyme using flurogenic Ac-LeuGlyLys (Ac)-AMC as substrate after 15 to 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed