BDBM50620120 ARV-110::ARV110::Arv-110::BAVDEGALUTAMIDE::Bavdegalutamide

SMILES Fc1cc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2cc1N1CCN(CC2CCN(CC2)c2ccc(nn2)C(=O)N[C@H]2CC[C@@H](CC2)Oc2ccc(C#N)c(Cl)c2)CC1

InChI Key InChIKey=CLCTZVRHDOAUGJ-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50620120   

TargetAndrogen receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50620120(BAVDEGALUTAMIDE | Bavdegalutamide | Arv-110 | ARV-...)
Affinity DataEC50:  3.60nMAssay Description:Induction of androgen receptor degradation in human VCaP cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAndrogen receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50620120(BAVDEGALUTAMIDE | Bavdegalutamide | Arv-110 | ARV-...)
Affinity DataEC50:  5.5nMAssay Description:Induction of androgen receptor degradation in human LNCaP cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAndrogen receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50620120(BAVDEGALUTAMIDE | Bavdegalutamide | Arv-110 | ARV-...)
Affinity DataEC50: <1nMAssay Description:Induction of AR degradation in human LNCaP cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAndrogen receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50620120(BAVDEGALUTAMIDE | Bavdegalutamide | Arv-110 | ARV-...)
Affinity DataEC50: <1nMAssay Description:Induction of AR degradation in human VCaP cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed