BDBM50432714 AM4054::CHEMBL2348462

SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@H](CO)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2

InChI Key

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50432714   

TargetCannabinoid receptor 1(Human)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50432714(AM4054 | CHEMBL2348462)
Affinity DataEC50:  96nMAssay Description:Agonist activity at human CB1 receptor transfected in human U2OS cells assessed as beta-arrestin2-GFP aggregation after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50432714(AM4054 | CHEMBL2348462)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at human CB1 receptor transfected in HEK293 cells assessed as reduction in forskolin-stimulated cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50432714(AM4054 | CHEMBL2348462)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]CP-55940 from rat CB1 receptor expressed in rat brain membrane by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50432714(AM4054 | CHEMBL2348462)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK293 cell membrane by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Mouse)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50432714(AM4054 | CHEMBL2348462)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]CP-55940 from mouse CB2 receptor expressed in mouse spleen membrane by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed