BDBM33408 AG1295::CHEMBL7724::cid_2048

SMILES Cc1cc2ncc(nc2cc1C)-c1ccccc1

InChI Key InChIKey=FQNCLVJEQCJWSU-UHFFFAOYSA-N

Data  9 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 33408   

TargetPlatelet-derived growth factor receptor beta(Human)
Duquesne University

LigandPNGBDBM33408(cid_2048 | CHEMBL7724 | AG1295)
Affinity DataIC50: 6.20E+3nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM33408(cid_2048 | CHEMBL7724 | AG1295)
Affinity DataEC50:  6.75E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM33408(cid_2048 | CHEMBL7724 | AG1295)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM33408(cid_2048 | CHEMBL7724 | AG1295)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM33408(cid_2048 | CHEMBL7724 | AG1295)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of endogenous FLT3 autophosphorylation in EOL1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM33408(cid_2048 | CHEMBL7724 | AG1295)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of endogenous PDGFRbeta autophosphorylation in Swiss 3T3 fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Duquesne University

LigandPNGBDBM33408(cid_2048 | CHEMBL7724 | AG1295)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of PDGFRbeta expressed in human tumor cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Duquesne University

LigandPNGBDBM33408(cid_2048 | CHEMBL7724 | AG1295)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Duquesne University

LigandPNGBDBM33408(cid_2048 | CHEMBL7724 | AG1295)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of PDGFBB-induced PDGFRbeta autophosphorylation in human SF539 cells incubated for 60 mins prior to PDGFBB-induction measured after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Duquesne University

LigandPNGBDBM33408(cid_2048 | CHEMBL7724 | AG1295)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of PDGF-BB-induced PDGFR beta phosphorylation in human SF539 cells overexpressing PDGFR beta pretreated for 60 mins prior to PDGF-BB addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed