BDBM50377863 AG-525::CHEMBL257156

SMILES COc1cc2CCN(C)[C@@H](CCC[C@@H]3N(C)CCc4cc(OC)c(OC)cc34)c2cc1OC

InChI Key InChIKey=MULXFGRQRGZGNO-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50377863   

LigandPNGBDBM50377863(AG-525 | CHEMBL257156)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of SK2 expressed in CHO FlipIn cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
LigandPNGBDBM50377863(AG-525 | CHEMBL257156)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of SK1 expressed in CHO FlipIn cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
LigandPNGBDBM50377863(AG-525 | CHEMBL257156)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of SK3 expressed in CHO FlipIn cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
LigandPNGBDBM50377863(AG-525 | CHEMBL257156)
Affinity DataKi:  277nMAssay Description:Displacement of [125I]apamin from SK2 (unknown origin) expressed in HEK293 cells assessed as inhibition constant incubated for 1 hr by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
LigandPNGBDBM50377863(AG-525 | CHEMBL257156)
Affinity DataKi:  370nMAssay Description:Displacement of [125I]apamin from SK3 (unknown origin) expressed in HEK293 cells assessed as inhibition constant incubated for 1 hr by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed