BDBM50197038 6-(5-chloro-2,4-dimethoxyphenethyl)-6-cyclopentyl-3-(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-ylthio)-4-hydroxy-5,6-dihydropyran-2-one::AG-21541::CHEMBL222231

SMILES COc1cc(OC)c(CCC2(CC(=O)C(Sc3nc4nc(C)cc(C)n4n3)C(=O)O2)C2CCCC2)cc1Cl

InChI Key InChIKey=PVOJFRAJCNHPSI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50197038   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50197038(AG-21541 | 6-(5-chloro-2,4-dimethoxyphenethyl)-6-c...)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant HCV 1b BK NS5B polymerase by primer/template-directed transcription assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed