BDBM701970 ACV-2-203::US12129248, Compound ACV-64

SMILES O=C(O)c3ccc(c2csc(N/N=C/c1ccc(O)c(O)c1O)n2)cc3

InChI Key InChIKey=NUMSYAMXDWDDFM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 701970   

TargetChromobox protein homolog 2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM701970(ACV-2-203 | US12129248, Compound ACV-64)
Affinity DataIC50: 5.22E+3nMAssay Description:The protocol for the CBX7 AlphaScreen was as follows: a standard alpha buffer (50 mM HEPES, 150 mM NaCl, 0.1% w/v BSA, 0.01% w/v Tween20) at pH 8.0 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2025
Entry Details
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TargetChromobox protein homolog 7(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM701970(ACV-2-203 | US12129248, Compound ACV-64)
Affinity DataIC50: 0.0290nMAssay Description:The protocol for the CBX7 Fluorescence Polarization assay is as follows: A standard FP buffer (20 mM Tris, 250 mM NaCl, 0.01% w/v Tween20) at pH 8.0 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2025
Entry Details
Go to US Patent