BDBM701959 ACV-2-155::US12129248, Compound ACV-53

SMILES COc1ccc(NC(=O)Nc2ncc(CC(=O)Nc3ccc(N4CCCC4)cc3)s2)cc1OC

InChI Key InChIKey=IWFTXZGWAOLDQH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 701959   

TargetChromobox protein homolog 2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM701959(ACV-2-155 | US12129248, Compound ACV-53)
Affinity DataIC50: 1.25E+4nMAssay Description:The protocol for the CBX7 AlphaScreen was as follows: a standard alpha buffer (50 mM HEPES, 150 mM NaCl, 0.1% w/v BSA, 0.01% w/v Tween20) at pH 8.0 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2025
Entry Details
Go to US Patent

TargetChromobox protein homolog 7(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM701959(ACV-2-155 | US12129248, Compound ACV-53)
Affinity DataIC50: 0.0480nMAssay Description:The protocol for the CBX7 Fluorescence Polarization assay is as follows: A standard FP buffer (20 mM Tris, 250 mM NaCl, 0.01% w/v Tween20) at pH 8.0 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2025
Entry Details
Go to US Patent