BDBM701958 ACV-2-154::US12129248, Compound ACV-52

SMILES O=C(Cc1cnc(NC(=O)Nc2ccc(CF)cc2)s1)Nc1ccc(N2CCCC2)cc1

InChI Key InChIKey=QYBXLLXUIAVUKQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 701958   

TargetChromobox protein homolog 2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM701958(ACV-2-154 | US12129248, Compound ACV-52)
Affinity DataIC50: 6.58E+3nMAssay Description:The protocol for the CBX7 AlphaScreen was as follows: a standard alpha buffer (50 mM HEPES, 150 mM NaCl, 0.1% w/v BSA, 0.01% w/v Tween20) at pH 8.0 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2025
Entry Details
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TargetChromobox protein homolog 7(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM701958(ACV-2-154 | US12129248, Compound ACV-52)
Affinity DataIC50: 0.00900nMAssay Description:The protocol for the CBX7 Fluorescence Polarization assay is as follows: A standard FP buffer (20 mM Tris, 250 mM NaCl, 0.01% w/v Tween20) at pH 8.0 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2025
Entry Details
Go to US Patent