BDBM50049753 3-((R)-1-Azetidin-2-ylmethoxy)-pyridine::3-((S)-1-Pyrrolidin-2-ylmethoxy)-pyridine::3-((S)-Azetidin-2-yloxy)-pyridine::3-(Pyrrolidin-2-ylmethoxy)-pyridine(A-85380)::A-85380::CHEMBL262769

SMILES C(Oc1cccnc1)[C@H]1CCN1

InChI Key InChIKey=XKFMBGWHHBCWCD-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50049753   

TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50049753(A-85380 | 3-(Pyrrolidin-2-ylmethoxy)-pyridine(A-85...)
Affinity DataEC50:  1.10E+3nMAssay Description:Functional activation of human sympathetic ganglionic type nAChRs in IMR-32 cells containing alpha-3 subtypeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50049753(A-85380 | 3-(Pyrrolidin-2-ylmethoxy)-pyridine(A-85...)
Affinity DataEC50:  3.60E+4nMAssay Description:Compound was evaluated for functional activation from channel currents at human Nicotinic acetylcholine receptor alpha-7 expressed in oocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit alpha(Pacific electric ray)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50049753(A-85380 | 3-(Pyrrolidin-2-ylmethoxy)-pyridine(A-85...)
Affinity DataKi:  384nMAssay Description:Compound was evaluated for its ability to displace [125 I]alpha-bungarotoxin (alpha-BgT) from torpedo alpha1-beta1-gamma1 electroplaxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50049753(A-85380 | 3-(Pyrrolidin-2-ylmethoxy)-pyridine(A-85...)
Affinity DataKi:  1.28E+3nMAssay Description:Compound was evaluated for its ability to displace [125I]alpha-bungarotoxin (alpha-BgT) from K28 cells expressing human Nicotinic acetylcholine recep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed