BDBM50189633 1-hydroxy-1-(4-(2-(4-phenoxyphenoxy)thiazol-5-yl)but-3-yn-2-yl)urea::A-80040::CHEMBL378186

SMILES CC(C#Cc1cnc(Oc2ccc(Oc3ccccc3)cc2)s1)N(O)C(N)=O

InChI Key InChIKey=MCMUCDFOFIZPSA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50189633   

TargetAcetyl-CoA carboxylase 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189633(1-hydroxy-1-(4-(2-(4-phenoxyphenoxy)thiazol-5-yl)b...)
Affinity DataIC50: 75nMAssay Description:Inhibition of ACC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189633(1-hydroxy-1-(4-(2-(4-phenoxyphenoxy)thiazol-5-yl)b...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ACC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189633(1-hydroxy-1-(4-(2-(4-phenoxyphenoxy)thiazol-5-yl)b...)
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant ACC2 expressed in baculovirus/sf9 systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189633(1-hydroxy-1-(4-(2-(4-phenoxyphenoxy)thiazol-5-yl)b...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed