BDBM50652789 A-486

SMILES CNC(=O)Nc1ccc2c(c1)[C@@]1(CC2)OC(=O)N(CC(=O)N(Cc2ccc(F)cc2)[C@@H](C)C(F)(F)F)C1=O

InChI Key InChIKey=MTTJOZOOUCZVHO-UHFFFAOYSA-N

Data  3 IC50  1 Kd  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50652789   

TargetHistone acetyltransferase p300(Human)
AbbVie

Curated by ChEMBL
LigandPNGBDBM50652789(A-486)
Affinity DataKd:  2.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
AbbVie

Curated by ChEMBL
LigandPNGBDBM50652789(A-486)
Affinity DataIC50: 5.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50652789(A-486)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50652789(A-486)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50652789(A-486)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
AbbVie

Curated by ChEMBL
LigandPNGBDBM50652789(A-486)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCREB-binding protein(Human)
AbbVie

Curated by ChEMBL
LigandPNGBDBM50652789(A-486)
Affinity DataIC50: 9.03E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed