BDBM50370569 A-349,821::A-349821

SMILES C[C@H]1CC[C@H](C)N1CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCOCC1

InChI Key InChIKey=CFUHKRLMDNFZED-UHFFFAOYSA-N

Data  17 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50370569   

TargetHistamine H3 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50370569(A-349821 | A-349,821)
Affinity DataKi:  0.398nMAssay Description:Binding affinity to rat cortical histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50370569(A-349821 | A-349,821)
Affinity DataKi:  0.490nMAssay Description:Binding affinity for human recombinant H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50370569(A-349821 | A-349,821)
Affinity DataKi:  1.58nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50370569(A-349821 | A-349,821)
Affinity DataKi:  1.70nMAssay Description:Binding affinity towards rat cortical H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50370569(A-349821 | A-349,821)
Affinity DataKi:  2nMAssay Description:Binding affinity to histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50370569(A-349821 | A-349,821)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]RAMH from human histamine H3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50370569(A-349821 | A-349,821)
Affinity DataKi:  933nMAssay Description:Binding affinity towards human muscarinic M2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50370569(A-349821 | A-349,821)
Affinity DataKi:  1.62E+3nMAssay Description:Binding affinity towards human Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50370569(A-349821 | A-349,821)
Affinity DataKi:  1.62E+3nMAssay Description:Binding affinity towards human muscarinic M1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50370569(A-349821 | A-349,821)
Affinity DataKi:  1.66E+3nMAssay Description:Binding affinity towards human muscarinic M3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50370569(A-349821 | A-349,821)
Affinity DataKi:  2.34E+3nMAssay Description:Binding affinity towards human histaminergic (H1) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50370569(A-349821 | A-349,821)
Affinity DataKi:  3.55E+3nMAssay Description:Binding affinity towards human UPTK-Serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50370569(A-349821 | A-349,821)
Affinity DataKi:  4.90E+3nMAssay Description:Binding affinity towards human UPTK-DA transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50370569(A-349821 | A-349,821)
Affinity DataKi:  9.77E+3nMAssay Description:Binding affinity towards human D4.2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50370569(A-349821 | A-349,821)
Affinity DataKi:  9.77E+3nMAssay Description:Binding affinity towards human UPTK-NE transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50370569(A-349821 | A-349,821)
Affinity DataKi:  1.00E+4nMAssay Description:Binding affinity towards human histaminergic (H2) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50370569(A-349821 | A-349,821)
Affinity DataKi:  1.00E+4nMAssay Description:Binding affinity towards human histaminergic (H4) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed