BDBM59154 5739991

SMILES [O-][N+](=O)c1ccc(cc1)N1C(=S)S\C(=C/c2ccc(Br)o2)C1=O

InChI Key InChIKey=ALKRRWSPLNEMPF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 59154   

TargetCoagulation factor VIII(Human)
University of Washington

LigandPNGBDBM59154(5739991)
Affinity DataIC50: 4.63E+3nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandPNGBDBM59154(5739991)
Affinity DataIC50: 1.04E+4nMpH: 8.0Assay Description:Inhibition of factor VIII ELISA. The interaction between factor VIII and PS was measured by using an enzyme-linked immunoadsorbent assay (ELISA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed
TargetCoagulation factor VIII(Human)
University of Washington

LigandPNGBDBM59154(5739991)
Affinity DataIC50: 1.17E+4nMpH: 7.9Assay Description:Inhibition of factor X activation assay. A commercially available chromogenic assay that measures the rate of factor X activation to measure inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2011
Entry Details Article
PubMed