BDBM50085972 5-MeO-DMT::CHEMBL7143::[2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimethyl-amine::[2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimethyl-amine (C2H2O)::[2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimethyl-ammonium

SMILES COc1ccc2[nH]c(C)c(CCN(C)C)c2c1

InChI Key InChIKey=ACEHBQPPDDGCGZ-UHFFFAOYSA-N

Data  55 KI  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 61 hits for monomerid = 50085972   

Target5-hydroxytryptamine receptor 2C(Human)
University of Oklahoma

LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataEC50:  23.6nMAssay Description:Data from pone.0009019.s006.doc, supplement tables.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Oklahoma

LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataEC50:  49.6nMAssay Description:Data from pone.0009019.s006.doc, supplement tables.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Oklahoma

LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataEC50:  183nMAssay Description:Data from pone.0009019.s006.doc, supplement tables.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Oklahoma

LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataEC50:  4.23nMAssay Description:Data from pone.0009019.s006.doc, supplement tables.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Oklahoma

LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataEC50:  56.9nMAssay Description:Data from pone.0009019.s006.doc, supplement tables.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Oklahoma

LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataEC50:  2.65nMAssay Description:Data from pone.0009019.s006.doc, supplement tables.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Oklahoma

LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi:  60nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Oklahoma

LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi:  60nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Oklahoma

LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi:  60nMAssay Description:Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Oklahoma

LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi:  80nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptor expressed in HEK 293 human embryonic kidney cells, [3H]-lysergic acid diethylamide as radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Oklahoma

LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi:  89nMAssay Description:Binding affinity as displacement of [3H]5-HT binding to 5-hydroxytryptamine 6 receptor in HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi:  145nMAssay Description:Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi:  145nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi:  200nMAssay Description:Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi:  200nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi:  250nMAssay Description:Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi:  250nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
State University of Groningen

Curated by ChEMBL
LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi:  1.12E+3nMAssay Description:Binding affinity at rat 5-hydroxytryptamine 7 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi:  1.26E+3nMAssay Description:Binding affinity of compound towards rodent 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1E(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi:  1.80E+3nMAssay Description:Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 1E receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1E(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi:  1.80E+3nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi:  4.02E+3nMAssay Description:Compound was evaluated for its binding affinity towards rat 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Oklahoma

LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi:  4.02E+3nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi:  6.38E+3nMAssay Description:Compound was evaluated for its binding affinity towards human NET (norepinephrine) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi:  6.38E+3nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
University of Oklahoma

LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for its binding affinity towards rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
University of Oklahoma

LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetVasopressin V1a receptor(Human)
University of Oklahoma

LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetVasopressin V1a receptor(Human)
University of Oklahoma

LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetVasopressin V1b receptor(Human)
University of Oklahoma

LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetGlutamate receptor 4(Human)
University of Oklahoma

LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Oklahoma

LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
University of Oklahoma

LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for its binding affinity towards human serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
University of Oklahoma

LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
University of Oklahoma

LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
University of Oklahoma

LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetCarnitine O-palmitoyltransferase 2, mitochondrial(Human)
University of Oklahoma

LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Oklahoma

LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetD(1B) dopamine receptor(Human)
University of Oklahoma

LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Oklahoma

LigandPNGBDBM50085972([2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
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