BDBM82302 5-BENZYLOXYTRYPTAMINE::5-BZT::CAS_20776-45-8::CHEMBL1288652

SMILES NCCc1c[nH]c2ccc(OCc3ccccc3)cc12

InChI Key InChIKey=WKPDXBXNJWWWGQ-UHFFFAOYSA-N

Data  4 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 82302   

LigandPNGBDBM82302(5-BENZYLOXYTRYPTAMINE | CHEMBL1288652 | CAS_20776-...)
Affinity DataIC50: 340nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
LigandPNGBDBM82302(5-BENZYLOXYTRYPTAMINE | CHEMBL1288652 | CAS_20776-...)
Affinity DataIC50: 660nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM82302(5-BENZYLOXYTRYPTAMINE | CHEMBL1288652 | CAS_20776-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human LTA4H epoxide hydrolase activity using LTA4 as substrate incubated for 15 mins prior to substrate addition measured after 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM82302(5-BENZYLOXYTRYPTAMINE | CHEMBL1288652 | CAS_20776-...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human LTA4H aminopeptidase activity using Ala-p-nitroanilide as substrate incubated for 2 mins prior to substrate addition measured for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM82302(5-BENZYLOXYTRYPTAMINE | CHEMBL1288652 | CAS_20776-...)
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of human nonpancreatic secretory phospholipase A2 using 1,2-dimyristoyl-sn-glycero-3-phosphocholine as substrate after 10 mins by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM82302(5-BENZYLOXYTRYPTAMINE | CHEMBL1288652 | CAS_20776-...)
Affinity DataKi:  110nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM82302(5-BENZYLOXYTRYPTAMINE | CHEMBL1288652 | CAS_20776-...)
Affinity DataKi:  110nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Guinea pig)
Syntex Discovery Research

Curated by PDSP Ki Database
LigandPNGBDBM82302(5-BENZYLOXYTRYPTAMINE | CHEMBL1288652 | CAS_20776-...)
Affinity DataKi:  257nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM82302(5-BENZYLOXYTRYPTAMINE | CHEMBL1288652 | CAS_20776-...)
Affinity DataKi:  295nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2012
Entry Details Article
PubMed