BDBM91605 5'::alpha7 agonists 5'

SMILES Cn1c2ccccc2c(OCc2cnnn2CCC[N+]2(C)CCCC2)cc1=O

InChI Key InChIKey=KKLXBYQXIXRKET-UHFFFAOYSA-N

Data  5 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 91605   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of California San Diego

LigandPNGBDBM91605(5' | alpha7 agonists 5')
Affinity DataEC50:  2.00E+3nMpH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2012
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of California San Diego

LigandPNGBDBM91605(5' | alpha7 agonists 5')
Affinity DataKi:  600nM ΔG°:  -8.34kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2012
Entry Details Article
PubMed
TargetSoluble acetylcholine receptor(California sea hare)
University of California San Diego

LigandPNGBDBM91605(5' | alpha7 agonists 5')
Affinity DataKi:  800nM ΔG°:  -8.17kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2012
Entry Details Article
PubMed
TargetSoluble acetylcholine receptor(California sea hare)
University of California San Diego

LigandPNGBDBM91605(5' | alpha7 agonists 5')
Affinity DataKi:  1.40E+3nM ΔG°:  -7.85kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Mouse)
University of California San Diego

LigandPNGBDBM91605(5' | alpha7 agonists 5')
Affinity DataKi: >3.00E+4nM ΔG°: >-6.41kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
University of California San Diego

LigandPNGBDBM91605(5' | alpha7 agonists 5')
Affinity DataKi:  4.00E+4nM ΔG°:  -6.24kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2012
Entry Details Article
PubMed