BDBM50333128 ((2S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate::3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE::3'-dCTP::CHEMBL480328

SMILES Nc1ccn([C@@H]2O[C@H](CO[P@@](O)(=O)O[P@@](O)(=O)OP(O)(O)=O)C[C@H]2O)c(=O)n1

InChI Key InChIKey=CHKFLBOLYREYDO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50333128   

TargetDNA-directed RNA polymerase II subunit RPB1(Human)
Pharmasset

Curated by ChEMBL
LigandPNGBDBM50333128(((2S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4-...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human RNA polymerase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepacivirus C)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50333128(((2S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4-...)
Affinity DataIC50: 770nMAssay Description:Inhibition of HCV NS5B polymerase S282T mutant assessed as blocking of full length RNA product formation by single-nucleotide incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed