BDBM50014406 2-Me 5-HT::2-Methyl-5-hydroxytryptamine::2-methyl-5-HT::2-methylserotonin::3-(2-aminoethyl)-2-methyl-1H-indol-5-ol::5-HT,2-Me::CHEMBL266591

SMILES Cc1[nH]c2ccc(O)cc2c1CCN

InChI Key InChIKey=WYWNEDARFVJQSG-UHFFFAOYSA-N

Data  42 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 45 hits for monomerid = 50014406   

Target5-hydroxytryptamine receptor 3A/3B(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataIC50: 779nMAssay Description:Inhibition of [3H]BRL-43694 binding to 5-hydroxytryptamine 3 receptor of rat cortical homogenate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataIC50: 646nMAssay Description:Compound was evaluated for the displacement of [3H]Q-ICS-205-930 from 5-HT3 recognition sites in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2014
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataIC50: 646nMAssay Description:Compound was evaluated for the displacement of [3H]-Q-ICS 205-930 binding to 5-hydroxytryptamine 3 receptor in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2014
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  46nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptor expressed in HEK 293 human embryonic kidney cells, [3H]-lysergic acid diethylamide as radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  46nMAssay Description:Binding affinity towards 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  52.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Cerebrus

Curated by PDSP Ki Database
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  170nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Cerebrus

Curated by PDSP Ki Database
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  197nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Rat)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  282nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Rat)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  284nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Rat)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  316nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine 1D receptor(Bovine)
Synaptic Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  398nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Mouse)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  398nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  400nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 6 receptor was evaluated using [125I]-2-iodo LSD as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Synaptic Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  413nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Synaptic Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  417nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  513nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  520nMAssay Description:Binding affinity was determined against 5-hydroxytryptamine 1B receptor was determined in male Sprague-Dawley rat brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  562nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  650nMAssay Description:Binding affinity was determined against 5-hydroxytryptamine 1C receptor was determined in male Sprague-Dawley rat brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1E(Human)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  813nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1E(Human)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  817nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  851nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Synaptic Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  860nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  915nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Mouse)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  995nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity was determined against 5-hydroxytryptamine 1A receptor was determined in male Sprague-Dawley rat brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  1.20E+3nMAssay Description:Compound was evaluated for its binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Cerebrus

Curated by PDSP Ki Database
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  1.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  1.22E+3nMAssay Description:In vitro displacement of [3H]ICS-205-930 from 5-hydroxytryptamine 3 receptor in cultured NG-108-15 rat glioma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Synaptic Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  1.22E+3nMAssay Description:Binding affinity was determined against 5-hydroxytryptamine 1D receptor in bovine caudate homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  1.26E+3nMAssay Description:Binding affinity of compound towards rodent 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Guinea pig)
Syntex Discovery Research

Curated by PDSP Ki Database
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  1.26E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  1.37E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 3A(Mouse)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  1.43E+3nMAssay Description:The binding affinity was measured for 5-hydroxytryptamine 3 receptor on NG 108-15 cell line of mouse neuroblastoma-glioma cells in presence of [3H]5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Cerebrus

Curated by PDSP Ki Database
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  2.40E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  2.51E+3nMAssay Description:Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Mouse)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi:  6.61E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1E(Human)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity was determined against 5-hydroxytryptamine 1E receptor in human cortical homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 5A(Mouse)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards mouse 5-hydroxytryptamine 5A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for rodent 5-hydroxytryptamine 5A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50014406(CHEMBL266591 | 2-Methyl-5-hydroxytryptamine | 2-Me...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity was determined against 5-hydroxytryptamine 2 receptor from male Sprague-Dawley rat brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed