BDBM12467 (2S)-1-(2-{[(4-fluorophenyl)methyl]amino}acetyl)pyrrolidine-2-carbonitrile::1-{[(4-Fluorobenzyl)amino]acetyl}-2-pyrrolidinecarbonitrile::17c::Amide Analogue 49

SMILES Fc1ccc(CNCC(=O)N2CCC[C@H]2C#N)cc1

InChI Key InChIKey=NTIOVEPRZJLUHB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12467   

TargetDipeptidyl peptidase 4(Human)
University of Antwerp

LigandPNGBDBM12467(17c | 1-{[(4-Fluorobenzyl)amino]acetyl}-2-pyrrolid...)
Affinity DataIC50: 3.70E+3nMAssay Description:The DPP inhibition was measured by monitoring the cleavage of chromogenic substrate in the presence of each inhibitor compound. IC50 value was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
University of Antwerp

LigandPNGBDBM12467(17c | 1-{[(4-Fluorobenzyl)amino]acetyl}-2-pyrrolid...)
Affinity DataIC50: 2.55E+4nMAssay Description:The DPP inhibition was measured by monitoring the cleavage of chromogenic substrate in the presence of each inhibitor compound. IC50 value was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2006
Entry Details Article
PubMed