BDBM12465 (2S)-1-{2-[(2-phenylethyl)amino]acetyl}pyrrolidine-2-carbonitrile::1-{[(2-Phenylethyl)amino]acetyl}-2-pyrrolidinecarbonitrile::17a::Amide Analogue 47::CHEMBL96942

SMILES O=C(CNCCc1ccccc1)N1CCC[C@H]1C#N

InChI Key InChIKey=GUAUWCMBKUFPRX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 12465   

TargetDipeptidyl peptidase 4(Human)
University of Antwerp

LigandPNGBDBM12465(1-{[(2-Phenylethyl)amino]acetyl}-2-pyrrolidinecarb...)
Affinity DataIC50: 2.13E+3nMAssay Description:The DPP inhibition was measured by monitoring the cleavage of chromogenic substrate in the presence of each inhibitor compound. IC50 value was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
University of Antwerp

LigandPNGBDBM12465(1-{[(2-Phenylethyl)amino]acetyl}-2-pyrrolidinecarb...)
Affinity DataIC50: 1.63E+4nMAssay Description:The DPP inhibition was measured by monitoring the cleavage of chromogenic substrate in the presence of each inhibitor compound. IC50 value was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
University of Antwerp

LigandPNGBDBM12465(1-{[(2-Phenylethyl)amino]acetyl}-2-pyrrolidinecarb...)
Affinity DataIC50: 305nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed