BDBM91631 16t::alpha7 agonists 16t

SMILES CN1[C@H]2CC[C@@H]1C[C@H](C2)n1cc(CNS(=O)(=O)c2ccc(cc2)[N+]([O-])=O)nn1

InChI Key

Data  6 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 91631   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of California San Diego

LigandPNGBDBM91631(16t | alpha7 agonists 16t)
Affinity DataEC50:  5.00E+3nMpH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2012
Entry Details Article
PubMed
TargetSoluble acetylcholine receptor(California sea hare)
University of California San Diego

LigandPNGBDBM91631(16t | alpha7 agonists 16t)
Affinity DataKi: >5.00E+3nM ΔG°: >-7.11kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2012
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of California San Diego

LigandPNGBDBM91631(16t | alpha7 agonists 16t)
Affinity DataKi: >5.00E+3nM ΔG°: >-7.11kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2012
Entry Details Article
PubMed
TargetSoluble acetylcholine receptor(California sea hare)
University of California San Diego

LigandPNGBDBM91631(16t | alpha7 agonists 16t)
Affinity DataKi: >5.00E+3nM ΔG°: >-7.11kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2012
Entry Details Article
PubMed
TargetSoluble acetylcholine receptor(California sea hare)
University of California San Diego

LigandPNGBDBM91631(16t | alpha7 agonists 16t)
Affinity DataKi: >5.00E+3nM ΔG°: >-7.11kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
University of California San Diego

LigandPNGBDBM91631(16t | alpha7 agonists 16t)
Affinity DataKi: >3.00E+4nM ΔG°: >-6.41kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Mouse)
University of California San Diego

LigandPNGBDBM91631(16t | alpha7 agonists 16t)
Affinity DataKi: >3.00E+4nM ΔG°: >-6.41kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2012
Entry Details Article
PubMed