BDBM50025735 (5Z,8Z,11Z,13E)-15-oxoicosa-5,8,11,13-tetraenoic acid::15-Kete::15-Oxo-ETE::CHEMBL418941

SMILES CCCCCC(=O)C=CC=CC\C=C/C\C=C/CCCC(O)=O

InChI Key InChIKey=YGJTUEISKATQSM-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50025735   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
University of California

Curated by ChEMBL
LigandPNGBDBM50025735((5Z,8Z,11Z,13E)-15-oxoicosa-5,8,11,13-tetraenoic a...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of rabbit reticulocyte 15-LOX by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50025735((5Z,8Z,11Z,13E)-15-oxoicosa-5,8,11,13-tetraenoic a...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human reticulocyte 15-lipoxygenase-2 by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50025735((5Z,8Z,11Z,13E)-15-oxoicosa-5,8,11,13-tetraenoic a...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human reticulocyte 15-lipoxygenase-1 by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50025735((5Z,8Z,11Z,13E)-15-oxoicosa-5,8,11,13-tetraenoic a...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human platelet 12-lipoxygenase by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50025735((5Z,8Z,11Z,13E)-15-oxoicosa-5,8,11,13-tetraenoic a...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human leukocyte 5-lipoxygenase by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
LigandPNGBDBM50025735((5Z,8Z,11Z,13E)-15-oxoicosa-5,8,11,13-tetraenoic a...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of rat basophilic leukemia-1 (RBL-1) 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50025735((5Z,8Z,11Z,13E)-15-oxoicosa-5,8,11,13-tetraenoic a...)
Affinity DataKi:  87nMAssay Description:Mixed type inhibition of human platelet 12-lipoxygenase assessed as equilibrium inhibitor constant of dissociation from enzyme by measuring 12-HpETE ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed