BDBM12461 (1R,S)-(2Z)-2-{1-Fluoro-2-[(4-fluorobenzyl)amino]ethylidene}cyclopentanecarbonitrile::(2Z)-2-(1-fluoro-2-{[(4-fluorophenyl)methyl]amino}ethylidene)cyclopentane-1-carbonitrile::11.7c/1::Fluoro-Olefin Analogue 43

SMILES F\C(CNCc1ccc(F)cc1)=C1\CCCC1C#N

InChI Key InChIKey=NREDMAXQKPQGQT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12461   

TargetDipeptidyl peptidase 4(Human)
University of Antwerp

LigandPNGBDBM12461((2Z)-2-(1-fluoro-2-{[(4-fluorophenyl)methyl]amino}...)
Affinity DataIC50: 1.00E+6nMAssay Description:The DPP inhibition was measured by monitoring the cleavage of chromogenic substrate in the presence of each inhibitor compound. IC50 value was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
University of Antwerp

LigandPNGBDBM12461((2Z)-2-(1-fluoro-2-{[(4-fluorophenyl)methyl]amino}...)
Affinity DataIC50: 8.73E+4nMAssay Description:The DPP inhibition was measured by monitoring the cleavage of chromogenic substrate in the presence of each inhibitor compound. IC50 value was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2006
Entry Details Article
PubMed