BDBM50261483 CHEMBL504973::YGGWL-NH2

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O

InChI Key InChIKey=GNLQCAGQAYEHAM-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50261483   

TargetMu-type opioid receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50261483(YGGWL-NH2 | CHEMBL504973)
Affinity DataIC50: 27.5nMAssay Description:Agonist activity at mu opioid receptor assessed as inhibition of forskolin-induced cAMP production in human SH-SY5Y cells pretreated for 24 hrs with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50261483(YGGWL-NH2 | CHEMBL504973)
Affinity DataIC50: 49.2nMAssay Description:Agonist activity at mu opioid receptor assessed as inhibition of forskolin-induced cAMP production in human SH-SY5Y cells pretreated for 24 hrs with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50261483(YGGWL-NH2 | CHEMBL504973)
Affinity DataKi:  12.1nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed