BDBM50337364 3-methoxy-4-hydroxybenzoic acid::4-Hydroxy-3-methoxy-benzoic acid::4-hydroxy-3-methoxybenzoic acid::4-hydroxyl-3-methoxybenzoic acid::CHEMBL120568::Vanilic acid::Vanillic acid (M2)

SMILES COc1cc(ccc1O)C(O)=O

InChI Key InChIKey=WKOLLVMJNQIZCI-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50337364   

TargetXanthine dehydrogenase/oxidase(Bovine)
Srtm University

LigandPNGBDBM50337364(4-hydroxy-3-methoxybenzoic acid | 4-Hydroxy-3-meth...)
Affinity DataIC50: 8.50E+3nMpH: 7.6 T: 2°CAssay Description:Inhibition of xanthine oxidase (XO) by each isolated phenolics was measured by following the decrease in the uric acid formation at 293nm at 25°...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetAlpha-glucosidase MAL12(Baker's yeast)
Srtm University

LigandPNGBDBM50337364(4-hydroxy-3-methoxybenzoic acid | 4-Hydroxy-3-meth...)
Affinity DataIC50: 2.05E+5nMAssay Description:The assay was performed using isolated phenolics from maize, and inhibition was determined according to previously described method.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetAlpha-glucosidase MAL12(Baker's yeast)
Srtm University

LigandPNGBDBM50337364(4-hydroxy-3-methoxybenzoic acid | 4-Hydroxy-3-meth...)
Affinity DataIC50: 3.00E+5nMpH: 7.0 T: 2°CAssay Description:α-glucosidase (25 μL, 0.2 U/mL), 25 μL of various concentrations of samples, and 175 μL of 50 mM sodium phosphate buffer (pH 7.0)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Daegu Haany University

Curated by ChEMBL
LigandPNGBDBM50337364(4-hydroxy-3-methoxybenzoic acid | 4-Hydroxy-3-meth...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of pig pancreatic lipase assessed as p-NPB hydrolysis by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetEnoyl-acyl-carrier protein reductase(malaria parasite P. falciparum)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50337364(4-hydroxy-3-methoxybenzoic acid | 4-Hydroxy-3-meth...)
Affinity DataIC50: 9.20E+5nMAssay Description:Inhibition of Plasmodium falciparum enoyl-ACP reductase assessed as oxidation of NADH to NAD+ after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Kinki University

Curated by ChEMBL
LigandPNGBDBM50337364(4-hydroxy-3-methoxybenzoic acid | 4-Hydroxy-3-meth...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate preincubated for 10 mins followed by enzyme addition measured after 20 mins by microp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50337364(4-hydroxy-3-methoxybenzoic acid | 4-Hydroxy-3-meth...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of CMG2 (40 to 217) C175A and R40C double mutant (unknown origin) interaction to full length PA E733C mutant expressed in Escherichia coli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed