BDBM50038066 (S)-2-((S)-2-Amino-3-methyl-butyrylamino)-3-(1H-indol-3-yl)-propionic acid::2-((S)-2-Amino-3-methyl-butyrylamino)-3-(S)-1H-indol-3-yl-propionic acid::CHEMBL91777::Val-Trp

SMILES CC(C)[C@H](N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O

InChI Key InChIKey=LZDNBBYBDGBADK-UHFFFAOYSA-N

Data  6 IC50  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50038066   

TargetAngiotensin-converting enzyme(Human)
Proteus Molecular Design

Curated by ChEMBL
LigandPNGBDBM50038066(Val-Trp | (S)-2-((S)-2-Amino-3-methyl-butyrylamino...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition against ACE.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Human)
Proteus Molecular Design

Curated by ChEMBL
LigandPNGBDBM50038066(Val-Trp | (S)-2-((S)-2-Amino-3-methyl-butyrylamino...)
Affinity DataIC50: 1.58E+6nMAssay Description:Inhibition of ACE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSolute carrier family 15 member 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50038066(Val-Trp | (S)-2-((S)-2-Amino-3-methyl-butyrylamino...)
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetSolute carrier family 15 member 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50038066(Val-Trp | (S)-2-((S)-2-Amino-3-methyl-butyrylamino...)
Affinity DataEC50:  4.00E+4nMAssay Description:Activation of human PEPT1 expressed in MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Human)
Proteus Molecular Design

Curated by ChEMBL
LigandPNGBDBM50038066(Val-Trp | (S)-2-((S)-2-Amino-3-methyl-butyrylamino...)
Affinity DataIC50: 1.58E+3nMAssay Description:Biological activity was measured against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Human)
Proteus Molecular Design

Curated by ChEMBL
LigandPNGBDBM50038066(Val-Trp | (S)-2-((S)-2-Amino-3-methyl-butyrylamino...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory activity on Angiotensin I converting enzyme (ACE) obtained from pig renal cortex and hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50038066(Val-Trp | (S)-2-((S)-2-Amino-3-methyl-butyrylamino...)
Affinity DataIC50: 6.57E+4nMAssay Description:Inhibition of DPP4 (unknown origin) using Gly-Pro-pNA as substrate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetThermolysin(Bacillus thermoproteolyticus)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50038066(Val-Trp | (S)-2-((S)-2-Amino-3-methyl-butyrylamino...)
Affinity DataKd:  1.23E+3nMAssay Description:Binding affinity against ThermolysinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed