BDBM50421717 TULOBUTEROL::Tulobuterol Hydrochloride

SMILES CC(C)(C)NCC(O)c1ccccc1Cl

InChI Key InChIKey=YREYLAVBNPACJM-UHFFFAOYSA-N

Data  1 IC50  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50421717   

TargetBeta-2 adrenergic receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50421717(Tulobuterol Hydrochloride | TULOBUTEROL)
Affinity DataKd:  130nMAssay Description:Apparent binding affinity constant to beta-2 adrenergic receptor determined using [3H]DHAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2014
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50421717(Tulobuterol Hydrochloride | TULOBUTEROL)
Affinity DataKd:  130nMAssay Description:Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50421717(Tulobuterol Hydrochloride | TULOBUTEROL)
Affinity DataKd:  66nMAssay Description:Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50421717(Tulobuterol Hydrochloride | TULOBUTEROL)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2019
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Northwest University

Curated by ChEMBL
LigandPNGBDBM50421717(Tulobuterol Hydrochloride | TULOBUTEROL)
Affinity DataKd:  6.80nMAssay Description:Displacement of [3H]-CGP12,177 from immobilized Halo tag-fused beta2 adrenoceptor (unknown origin) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed