BDBM50359629 TROLOX

SMILES Cc1c(C)c2OC(C)(CCc2c(C)c1O)C(O)=O

InChI Key InChIKey=GLEVLJDDWXEYCO-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50359629   

TargetAcetylcholinesterase(Human)
Instituto Superior Técnico

LigandPNGBDBM50359629(TROLOX)
Affinity DataIC50: 4.00E+6nMpH: 8.0Assay Description:AChE enzymatic activity was measured using an adaptation of the method previously described [Ingkaninan et al., J. Ethnopharmacol., 89:261-264]; 98 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto Superior Técnico

LigandPNGBDBM50359629(TROLOX)
Affinity DataIC50: 1.86E+5nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine as substrate preincubated for 5 mins followed by substrate addition measured every 2 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50359629(TROLOX)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human plasmatic BChE using butyrylthiocholine as substrate preincubated for 5 mins followed by substrate addition measured every 2 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Kyung Hee University Skin Biotechnology Center

Curated by ChEMBL
LigandPNGBDBM50359629(TROLOX)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of mushroom tyrosinase activity using L-tyrosin as substrate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50359629(TROLOX)
Affinity DataIC50: 1.31E+4nMAssay Description:Anti-oxidant activity in DPPH radical scavenging assay; n=3-4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50359629(TROLOX)
Affinity DataIC50: 150nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetDehydrogenase/reductase SDR family member 9(Human)
Institute For Natural Product Research and Infection Biology

Curated by ChEMBL
LigandPNGBDBM50359629(TROLOX)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of 3alphaHSDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Institute For Natural Product Research and Infection Biology

Curated by ChEMBL
LigandPNGBDBM50359629(TROLOX)
Affinity DataIC50: 130nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Institute For Natural Product Research and Infection Biology

Curated by ChEMBL
LigandPNGBDBM50359629(TROLOX)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of Xanthine oxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed