BDBM50089379 (2R,3R,4S,5R)-2-(3-Amino-5-methyl-5H-1,4,5,6,8-pentaaza-acenaphthylen-1-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol::(3R,4S,5R)-2-((R)-3-Amino-5-methyl-5H-1,4,5,6,8-pentaaza-acenaphthylen-1-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol::2-(3-Amino-5-methyl-5H-1,4,5,6,8-pentaaza-acenaphthylen-1-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol::CHEMBL331237::NSC-154020::TRICIRIBINE

SMILES Cn1nc(N)c2cn(C3O[C@H](CO)[C@H](O)[C@@H]3O)c3ncnc1c23

InChI Key InChIKey=HOGVTUZUJGHKPL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50089379   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50089379(CHEMBL331237 | (3R,4S,5R)-2-((R)-3-Amino-5-methyl-...)
Affinity DataIC50: 40nMAssay Description:Inhibitory concentration against human immunodeficiency virus type 1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed