BDBM50085363 CHEMBL60718::L-1-Tosylamido-2-phenylethyl chloromethyl ketone::N-Tosyl-L-phenylalanine chloromethyl ketone::N-Tosyl-L-phenylalanyl chloromethyl ketone::N-[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]-4-methylbenzenesulfonamide::TPCK::Tos-Phe-CH2Cl::Tosylphenylalanyl chloromethyl ketone::cid_439647::l-N-(alpha-(Chloroacetyl)phenethyl)-p-toluenesulfonamide

SMILES Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)CCl

InChI Key InChIKey=MQUQNUAYKLCRME-UHFFFAOYSA-N

Data  8 IC50

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50085363   

TargetProtein-arginine deiminase type-4(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50085363(N-Tosyl-L-phenylalanine chloromethyl ketone | CHEM...)
Affinity DataIC50: 1.30E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetPerilipin-1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50085363(N-Tosyl-L-phenylalanine chloromethyl ketone | CHEM...)
Affinity DataIC50: 1.87E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetPerilipin-5(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50085363(N-Tosyl-L-phenylalanine chloromethyl ketone | CHEM...)
Affinity DataIC50: 1.90E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetChymotrypsin-like elastase family member 2A(Pig)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085363(N-Tosyl-L-phenylalanine chloromethyl ketone | CHEM...)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibitory activity against porcine pancreatic elastase (PPE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin G(Human)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085363(N-Tosyl-L-phenylalanine chloromethyl ketone | CHEM...)
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibitory activity against human leukocyte cathepsin GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymase(Human)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085363(N-Tosyl-L-phenylalanine chloromethyl ketone | CHEM...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibitory activity against human serine protease chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085363(N-Tosyl-L-phenylalanine chloromethyl ketone | CHEM...)
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibitory activity against alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Pig)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085363(N-Tosyl-L-phenylalanine chloromethyl ketone | CHEM...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory activity against porcine pancreatic trypsin (TRP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed