BDBM50135840 (Phosphono-thiomorpholin-4-yl-methyl)-phosphonic acid::4-(Bis-phosphono-methyl)-thiomorpholin-4-ium::4-thiomorpholinylmethylene-1,1-bisphosphonate::CHEMBL299563::thiomorpholinomethylenediphosphonic acid

SMILES OP(O)(=O)C(N1CCSCC1)P(O)(O)=O

InChI Key InChIKey=RZULBGMWKROXRP-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135840   

TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135840((Phosphono-thiomorpholin-4-yl-methyl)-phosphonic a...)
Affinity DataIC50: 7.60E+4nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135840((Phosphono-thiomorpholin-4-yl-methyl)-phosphonic a...)
Affinity DataIC50: 7.59E+4nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase expressed as #NAME (M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135840((Phosphono-thiomorpholin-4-yl-methyl)-phosphonic a...)
Affinity DataKi:  7.30E+3nMAssay Description:Binding affinity towards farnesyl Pyrophosphate Synthase using [14C]- isopentenyl pyrophosphate as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed