BDBM50432960 KRN-568::NPS-R-568::Norcalcin::R-568::TECALCET HYDROCHLORIDE::Tecalcet HCl

SMILES C[C@H](c1cccc(c1)OC)NCCCc2ccccc2Cl

InChI Key InChIKey=ZVQUCWXZCKWZBP-UHFFFAOYSA-N

Data  1 EC50

PDB links: 6 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50432960   

TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50432960(Tecalcet HCl | NPS-R-568 | KRN-568 | R-568 | Norca...)
Affinity DataEC50:  80nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)