BDBM82219 CAS_52760-47-1::CHEMBL38120::CP-24441::Tametraline hydrochloride

SMILES CN[C@@H]1CC[C@@H](c2ccccc2)c2ccccc12

InChI Key InChIKey=NVXPZMLRGBVYQV-UHFFFAOYSA-N

Data  4 KI  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 82219   

LigandPNGBDBM82219(CHEMBL38120 | Tametraline hydrochloride | CAS_5276...)
Affinity DataIC50: 210nMAssay Description:Inhibition of dopamine uptake in synaptosomal preparation in rat corpus striatum, using [3H]dopamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM82219(CHEMBL38120 | Tametraline hydrochloride | CAS_5276...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of 5-HT uptake in synaptosomal preparation from rat corpus striatum, using [3H]5-HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM82219(CHEMBL38120 | Tametraline hydrochloride | CAS_5276...)
Affinity DataIC50: 40nMAssay Description:Inhibition of norepinephrine uptake in synaptosomal preparation fro rat hypothalamus, using [3H]norepinephrineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM82219(CHEMBL38120 | Tametraline hydrochloride | CAS_5276...)
Affinity DataIC50: 18nMAssay Description:Inhibition of norepinephrine uptake in synaptosomal preparation fro rat hypothalamus, using [3H]norepinephrineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM82219(CHEMBL38120 | Tametraline hydrochloride | CAS_5276...)
Affinity DataIC50: 370nMAssay Description:Inhibition of norepinephrine uptake in synaptosomal preparation fro rat hypothalamus, using [3H]norepinephrineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM82219(CHEMBL38120 | Tametraline hydrochloride | CAS_5276...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of dopamine uptake in synaptosomal preparation in rat corpus striatum, using [3H]dopamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM82219(CHEMBL38120 | Tametraline hydrochloride | CAS_5276...)
Affinity DataIC50: 150nMAssay Description:Inhibition of dopamine uptake in synaptosomal preparation in rat corpus striatum, using [3H]dopamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM82219(CHEMBL38120 | Tametraline hydrochloride | CAS_5276...)
Affinity DataIC50: 840nMAssay Description:Inhibition of 5-HT uptake in synaptosomal preparation from rat corpus striatum, using [3H]5-HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM82219(CHEMBL38120 | Tametraline hydrochloride | CAS_5276...)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of 5-HT uptake in synaptosomal preparation from rat corpus striatum, using [3H]5-HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetNorepinephrine transporter(Rat)
Pfizer

Curated by PDSP Ki Database
LigandPNGBDBM82219(CHEMBL38120 | Tametraline hydrochloride | CAS_5276...)
Affinity DataKi:  18nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2011
Entry Details
PubMed
LigandPNGBDBM82219(CHEMBL38120 | Tametraline hydrochloride | CAS_5276...)
Affinity DataKi:  150nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2011
Entry Details
PubMed
LigandPNGBDBM82219(CHEMBL38120 | Tametraline hydrochloride | CAS_5276...)
Affinity DataKi:  840nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2011
Entry Details
PubMed
LigandPNGBDBM82219(CHEMBL38120 | Tametraline hydrochloride | CAS_5276...)
Affinity DataKi:  4.70E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2011
Entry Details
PubMed