BDBM50002765 BM 13177::BM-13177::CHEMBL8273::Sulotroban::[4-(2-Benzenesulfonylamino-ethyl)-phenoxy]-acetic acid::[4-(2-Benzenesulfonylamino-ethyl)-phenoxy]-acetic acid (BM 13177)::[4-(2-Benzenesulfonylamino-ethyl)-phenoxy]-acetic acid(sulotroban)

SMILES OC(=O)COc1ccc(CCNS(=O)(=O)c2ccccc2)cc1

InChI Key InChIKey=XTNWJMVJVSGKLR-UHFFFAOYSA-N

Data  4 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50002765   

TargetThromboxane-A synthase(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50002765(BM 13177 | CHEMBL8273 | [4-(2-Benzenesulfonylamino...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory effect against thromboxane A2 synthase binding to bovine plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50002765(BM 13177 | CHEMBL8273 | [4-(2-Benzenesulfonylamino...)
Affinity DataIC50: 9.41E+4nMAssay Description:Activity against TXA2 synthase in bovine platelet microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50002765(BM 13177 | CHEMBL8273 | [4-(2-Benzenesulfonylamino...)
Affinity DataIC50: 1.50E+3nMAssay Description:Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane-A synthase(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50002765(BM 13177 | CHEMBL8273 | [4-(2-Benzenesulfonylamino...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for its inhibitory activity against Thromboxane A2 synthase obtained from bovine platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Carpibem

Curated by ChEMBL
LigandPNGBDBM50002765(BM 13177 | CHEMBL8273 | [4-(2-Benzenesulfonylamino...)
Affinity DataKi:  650nMAssay Description:Tested in vitro for inhibition constant against TXA2 / PGH-2 receptor using [125I]PTA-OH binding affinity to human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Carpibem

Curated by ChEMBL
LigandPNGBDBM50002765(BM 13177 | CHEMBL8273 | [4-(2-Benzenesulfonylamino...)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of the thromboxane A2 receptor assayed by binding to guinea pig platelets using [3H]U-46619 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Carpibem

Curated by ChEMBL
LigandPNGBDBM50002765(BM 13177 | CHEMBL8273 | [4-(2-Benzenesulfonylamino...)
Affinity DataKi:  1.30E+3nMAssay Description:Compound was tested for its binding affinity at Thromboxane A2 receptor by measuring its ability to displace [3H]U-46619 from guinea pig platelets at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Carpibem

Curated by ChEMBL
LigandPNGBDBM50002765(BM 13177 | CHEMBL8273 | [4-(2-Benzenesulfonylamino...)
Affinity DataKi:  1.40E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details
PubMed