BDBM50026604 1,2-Diphenyl-3,5-dioxo-4-(2-phenylsulfinylethyl)pyrazolidine::1,2-Diphenyl-4-(2'-phenylsulfinethyl)-3,5-pyrazolidinedione::1,2-diphenyl-4-[2-(phenylsulfinyl)ethyl]pyrazolidine-3,5-dione::4-(2-Benzenesulfinylethyl)-1,2-diphenylpyrazolidine-3,5-dione::Anturane (TN)::CHEMBL832::SULFINPYRAZONE::Sulfoxyphenylpyrazolidine

SMILES Oc1c(CCS(=O)c2ccccc2)c(=O)n(-c2ccccc2)n1-c1ccccc1

InChI Key InChIKey=AUMHDRMJJNZTPB-UHFFFAOYSA-N

Data  2 KI  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50026604   

TargetfMet-Leu-Phe receptor(Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM50026604(1,2-diphenyl-4-[2-(phenylsulfinyl)ethyl]pyrazolidi...)
Affinity DataIC50: 1.44E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2011
Entry Details
PCBioAssay
TargetN-formyl peptide receptor 2(Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM50026604(1,2-diphenyl-4-[2-(phenylsulfinyl)ethyl]pyrazolidi...)
Affinity DataIC50: 6.67E+4nMAssay Description:University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2011
Entry Details
PCBioAssay
TargetIntegrin alpha-4(Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM50026604(1,2-diphenyl-4-[2-(phenylsulfinyl)ethyl]pyrazolidi...)
Affinity DataEC50:  1.73E+4nMAssay Description:Assay Support: 1 X01 MH077638-01 MLSCN Assay for Allosteric Ligands for the VLA-4 Integrin PI: SKLAR, LARRY A University of New Mexico Assay Overview...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2011
Entry Details
PCBioAssay
TargetProstaglandin G/H synthase 1(Human)
Universidad De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50026604(1,2-diphenyl-4-[2-(phenylsulfinyl)ethyl]pyrazolidi...)
Affinity DataIC50: 5.09E+5nMAssay Description:Inhibition of thrombin-induced platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
The Chinese University of Hong Kong

Curated by ChEMBL
LigandPNGBDBM50026604(1,2-diphenyl-4-[2-(phenylsulfinyl)ethyl]pyrazolidi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human URAT1-mediated urate uptake in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Act

Curated by ChEMBL
LigandPNGBDBM50026604(1,2-diphenyl-4-[2-(phenylsulfinyl)ethyl]pyrazolidi...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human CYP51 expressed in Topp 3 cells by lanosterol demethylase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetfMet-Leu-Phe receptor(Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM50026604(1,2-diphenyl-4-[2-(phenylsulfinyl)ethyl]pyrazolidi...)
Affinity DataKi:  9.40E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2011
Entry Details
PCBioAssay
TargetN-formyl peptide receptor 2(Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM50026604(1,2-diphenyl-4-[2-(phenylsulfinyl)ethyl]pyrazolidi...)
Affinity DataKi: >4.03E+4nMAssay Description:University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2011
Entry Details
PCBioAssay