BDBM50197063 4,6-dioxoheptanoic acid::CHEMBL222824::succinylacetone

SMILES CC(=O)CC(=O)CCC(=O)O

InChI Key InChIKey=WYEPBHZLDUPIOD-UHFFFAOYSA-N

Data  9 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50197063   

TargetEgl nine homolog 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50197063(succinylacetone | 4,6-dioxoheptanoic acid | CHEMBL...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human PHD2 catalytic domain (181-426) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGamma-butyrobetaine dioxygenase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50197063(succinylacetone | 4,6-dioxoheptanoic acid | CHEMBL...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human BBOX1 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50197063(succinylacetone | 4,6-dioxoheptanoic acid | CHEMBL...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PHD2 expressed in Escherichia coli by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha inhibitor(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50197063(succinylacetone | 4,6-dioxoheptanoic acid | CHEMBL...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human FIH expressed in Escherichia coli by MALDI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysine-specific demethylase 6B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50197063(succinylacetone | 4,6-dioxoheptanoic acid | CHEMBL...)
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of human KDM6B catalytic domain expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysine-specific demethylase 5C(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50197063(succinylacetone | 4,6-dioxoheptanoic acid | CHEMBL...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human KDM5C catalytic domain expressed in Sf9 cells using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50197063(succinylacetone | 4,6-dioxoheptanoic acid | CHEMBL...)
Affinity DataIC50: 2.39E+4nMAssay Description:Inhibition of human KDM4E expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistone lysine demethylase PHF8(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50197063(succinylacetone | 4,6-dioxoheptanoic acid | CHEMBL...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human PHF8 expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysine-specific demethylase 2A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50197063(succinylacetone | 4,6-dioxoheptanoic acid | CHEMBL...)
Affinity DataIC50: 570nMAssay Description:Inhibition of human KDM2A expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed