BDBM50115661 CHEMBL320497::N,8-dihydroxy-8-(hydroxyamino)octanamide::N1,N8-dihydroxyoctanediamide::Octanedioic acid bis-hydroxyamide::Suberohydroxamic acid::Suberoic bis hydroxamic acid::Suberoyl bis hydroxamic acid

SMILES ONC(=O)CCCCCCC(=O)NO

InChI Key InChIKey=IDQPVOFTURLJPT-UHFFFAOYSA-N

Data  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50115661   

TargetHistone deacetylase 2b(Maize)
WestfäLische Wilhelms-UniversitäT MüNster

Curated by ChEMBL
LigandPNGBDBM50115661(Suberoic bis hydroxamic acid | N1,N8-dihydroxyocta...)
Affinity DataIC50: 320nMAssay Description:Inhibition of in vitro enzyme activity measured in a highly purified maize Histone deacetylase 2 preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50115661(Suberoic bis hydroxamic acid | N1,N8-dihydroxyocta...)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of HDAC1 (unknown origin) by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50115661(Suberoic bis hydroxamic acid | N1,N8-dihydroxyocta...)
Affinity DataIC50: 8.23E+3nMAssay Description:Inhibition of HDAC2 (unknown origin) by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50115661(Suberoic bis hydroxamic acid | N1,N8-dihydroxyocta...)
Affinity DataIC50: 2.03E+3nMAssay Description:Inhibition of HDAC6 (unknown origin) by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50115661(Suberoic bis hydroxamic acid | N1,N8-dihydroxyocta...)
Affinity DataIC50: 6.26E+4nMAssay Description:Inhibition of HDAC3 (unknown origin) by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50115661(Suberoic bis hydroxamic acid | N1,N8-dihydroxyocta...)
Affinity DataEC50:  1.10E+3nMAssay Description:Inhibition of HDAC6 in human HeLa cells assessed as inhibition of tubulin deacetylation incubated for overnight by cELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed