BDBM50298710 CHEMBL582937::Stylissadine B

SMILES NC1=N[C@]2(O)[C@H](N1)O[C@@H]1N=C(N)N[C@@]11[C@@H](O[C@H]3[C@H](CNC(=O)c4cc(Br)c(Br)[nH]4)[C@@H](CNC(=O)c4cc(Br)c(Br)[nH]4)[C@@H]4[C@]5(O)N=C(N)N[C@@H]5O[C@@H]5N=C(N)N[C@]345)[C@H](CNC(=O)c3cc(Br)c(Br)[nH]3)[C@@H](CNC(=O)c3cc(Br)c(Br)[nH]3)[C@@H]21

InChI Key InChIKey=YJHWJTAJYZABEV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50298710   

TargetP2X purinoceptor 7(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50298710(Stylissadine B | CHEMBL582937)
Affinity DataIC50: 1.80E+3nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced pore formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed