BDBM50252374 CHEMBL475118::Spheciosterol sulfate B

SMILES CC(C)C(CC[C@@H](C)[C@H]1CC[C@@]2(C)[C@@H]3C[C@H](OS([O-])(=O)=O)[C@H]4[C@@H](O)[C@H](OS([O-])(=O)=O)[C@H](C[C@]4(C)C3=CC[C@]12C)OS([O-])(=O)=O)C(C)=C

InChI Key InChIKey=DEHSPKKILBQXSX-UHFFFAOYSA-K

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50252374   

TargetProtein kinase C zeta type(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50252374(Spheciosterol sulfate B | CHEMBL475118)
Affinity DataIC50: 530nMAssay Description:Inhibition of PKCzeta by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTranscription factor p65(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50252374(Spheciosterol sulfate B | CHEMBL475118)
Affinity DataEC50:  1.20E+4nMAssay Description:Inhibition of IL1-induced NF-kappaB P65 activation in human osteoarthritic primary chondrocytes preincubated 2 hrs before addition of IL1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed