BDBM29278 CHEMBL310671::Garantose::SAC::Saccharimide::Saccharin
SMILES c1ccc2c(c1)C(=O)NS2(=O)=O
InChI Key InChIKey=CVHZOJJKTDOEJC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 112 hits for monomerid = 29278
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of BuChE (unknown origin) assessed as reduction in S-butyrylthiocholine chloride hydrolysis after 15 mins by Ellman methodMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
Sapienza University of Rome
Curated by ChEMBL
Sapienza University of Rome
Curated by ChEMBL
Affinity DataIC50: 5.10E+5nMAssay Description:Inhibition of human recombinant GST-PRMT1 expressed in BL21 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.10E+5nMAssay Description:Inhibition of Aspergillus nidulans recombinant GST-RmtA expressed in BL21 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of human recombinant carbonic anhydrase 7 expressed in Escherichia coli by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 incubated for 1 hr prior to testing measured for 10 to 100 secs by phenol red-based stopped-flow...More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of human carbonic anhydrase 7 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of human carbonic anhydrase 7 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 40.3nMAssay Description:Inhibition of Stylophora pistillata carbonic anhydrase by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 40.3nMAssay Description:Inhibition of cloned Stylophora pistillata alpha-CA expressed in human HEK293 cells by stopped-flow CO2 assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase(African malaria mosquito)
University of Tampere and Tampere University Hospital
Curated by ChEMBL
University of Tampere and Tampere University Hospital
Curated by ChEMBL
Affinity DataKi: 95nMAssay Description:Inhibition of Anopheles gambiae carbonic anhydrase pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 expressed in Escherichia coli L21-GOLD (DE3) incubated for 10 mins prior to testing by stopped-f...More data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Binding affinity to carbonic anhydrase 9 (unknown origin) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
Affinity DataKi: 103nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 expressed in Escherichia coli by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 103nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 103nMAssay Description:Inhibition of human recombinant CA9 by CO2 hydration stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 103nMAssay Description:Inhibition of human esterase activity of carbonic anhydrase 9 using 4-nitrophenylacetate as substrate after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 103nMAssay Description:Inhibition of recombinant human carbonic anhydrase-9 assessed as reduction in CO2 hydration preincubated for 10 mins measured for 5 to 10 secs by sto...More data for this Ligand-Target Pair
Affinity DataKi: 103nMAssay Description:Inhibition of human carbonic anhydrase 9 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 103nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 incubated for 1 hr prior to testing measured for 10 to 100 secs by phenol red-based stopped-flow...More data for this Ligand-Target Pair
Affinity DataKi: 103nMAssay Description:Inhibition of human carbonic anhydrase 9 catalytic site preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 103nMAssay Description:Inhibition of human carbonic anhydrase 9 catalytic site preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 104nMAssay Description:Inhibition of Stylophora pistillata carbonic anhydrase 2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 633nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 expressed in Escherichia coli by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 633nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 633nMAssay Description:Inhibition of human recombinant CA12 by CO2 hydration stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 633nMAssay Description:Inhibition of recombinant human carbonic anhydrase-12 assessed as reduction in CO2 hydration preincubated for 10 mins measured for 5 to 10 secs by st...More data for this Ligand-Target Pair
Affinity DataKi: 633nMAssay Description:Inhibition of human carbonic anhydrase 12 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 633nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 incubated for 1 hr prior to testing measured for 10 to 100 secs by phenol red-based stopped-flo...More data for this Ligand-Target Pair
Affinity DataKi: 633nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 633nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 650nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 expressed in Escherichia coli L21-GOLD (DE3) incubated for 10 mins prior to testing by stopped-...More data for this Ligand-Target Pair
Affinity DataKi: 736nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 751nMAssay Description:Inhibition of GST-tagged astrosclera willeyana Astrosclerin-3 expressed in Escherichia coli after 15 mins preincubation by stopped flow CO2 hydration...More data for this Ligand-Target Pair
Affinity DataKi: 773nMAssay Description:Inhibition of human recombinant carbonic anhydrase 14 expressed in Escherichia coli by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universita Degli Studi Di Firenze
Curated by ChEMBL
Universita Degli Studi Di Firenze
Curated by ChEMBL
Affinity DataKi: 792nMAssay Description:Inhibition of full length Mycobacterium tuberculosis H37Rv recombinant carbonic anhydrase 2 encoded by RV3588c by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase(Sulfurihydrogenibium sp. (strain YO3AOP1))
Universita Degli Studi Di Firenze
Curated by ChEMBL
Universita Degli Studi Di Firenze
Curated by ChEMBL
Affinity DataKi: 876nMAssay Description:Inhibition of recombinant Sulfurihydrogenibium yellowstonense YO3AOP1 carbonic anhydrase by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase, alpha family(Thiomicrospira crunogena (strain XCL-2))
Universita Degli Studi Di Firenze
Curated by ChEMBL
Universita Degli Studi Di Firenze
Curated by ChEMBL
Affinity DataKi: 933nMAssay Description:Inhibition of recombinant Thiomicrospira crunogena XCL-2 carbonic anhydrase by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 935nMAssay Description:Inhibition of human recombinant carbonic anhydrase 6 expressed in Escherichia coli by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 935nMAssay Description:Inhibition of human recombinant CA6 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.95E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 expressed in Escherichia coli by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.95E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.95E+3nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.95E+3nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 2 after 15 mins by CO2 hydrase assay at pH 7.5More data for this Ligand-Target Pair
Affinity DataKi: 5.95E+3nMpH: 7.5Assay Description:Inhibition of human recombinant carbonic anhydrase 2 at pH 7.5 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.95E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.95E+3nMAssay Description:Inhibition of human recombinant CA2 by CO2 hydration stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.95E+3nMAssay Description:Inhibition of human esterase activity of carbonic anhydrase 2 using 4-nitrophenylacetate as substrate after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5.95E+3nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.95E+3nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.95E+3nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair