BDBM50033767 3,3',4',5',7-pentahydroxy flavone::3,7,3',4',5'-Pentahydroxyflavone::3,7-Dihydroxy-2-(3,4,5-trihydroxy-phenyl)-chromen-4-one::3,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one::CHEMBL170405::NSC-407331::ROBINETIN::US11866416, Compound PAY

SMILES c1cc2c(cc1O)OC(=C(C2=O)O)c3cc(c(c(c3)O)O)O

InChI Key InChIKey=SOEDEYVDCDYMMH-UHFFFAOYSA-N

Data  1 KI  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50033767   

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50033767(CHEMBL170405 | 3,3',4',5',7-pentahydroxy flavone |...)
Affinity DataIC50: 1.60E+3nMAssay Description:IC50 was measured as concentration required to inhibit 50% of HIV-integrase integrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50033767(CHEMBL170405 | 3,3',4',5',7-pentahydroxy flavone |...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of cow milk xanthine oxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50033767(CHEMBL170405 | 3,3',4',5',7-pentahydroxy flavone |...)
Affinity DataIC50: 3.79E+4nMAssay Description:Inhibition of human CD38 using 20 uM 1, N6-etheno NAD+ as substrate by continuous fluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50033767(CHEMBL170405 | 3,3',4',5',7-pentahydroxy flavone |...)
Affinity DataIC50: 5.90E+3nMAssay Description:IC50 was measured as concentration required to inhibit 50% of HIV-integrase cleavageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetBiofilm regulatory protein A(Streptococcus mutans serotype c (strain ATCC 70061...)
Uab Research Foundation

US Patent
LigandPNGBDBM50033767(CHEMBL170405 | 3,3',4',5',7-pentahydroxy flavone |...)
Affinity DataIC50: 7.45E+4nMAssay Description:A previously reported zymographic assay was utilized for the investigation of Gtf enzymatic activity, as described in Example 1. A 1:100 in fresh 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
Go to US Patent

TargetMultidrug resistance-associated protein 1(Human)
The Hong Kong Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50033767(CHEMBL170405 | 3,3',4',5',7-pentahydroxy flavone |...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of MRP1 transfected in MDCK2 cells assessed as inhibition of calcein transportMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed