BDBM11053 CHEMBL386049::N-(4-sulfamoylphenyl)-2-sulfanylbenzamide::reduced monomeric thio of compound 5a::reduced thio H5a

SMILES c1ccc(c(c1)C(=O)Nc2ccc(cc2)S(=O)(=O)N)S

InChI Key InChIKey=MRLVIVXGUGNENL-UHFFFAOYSA-N

Data  10 KI

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 11053   

TargetCarbonic anhydrase 12(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM11053(reduced monomeric thio of compound 5a | CHEMBL3860...)
Affinity DataKi:  6.40nMAssay Description:Inhibition of human CA12 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11053(reduced monomeric thio of compound 5a | CHEMBL3860...)
Affinity DataKi:  9.10nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11053(reduced monomeric thio of compound 5a | CHEMBL3860...)
Affinity DataKi:  9.10nMAssay Description:Inhibition of human carbonic anhydrase 9 by stopped flow techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11053(reduced monomeric thio of compound 5a | CHEMBL3860...)
Affinity DataKi:  9.10nMAssay Description:Inhibition of human CA9 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11053(reduced monomeric thio of compound 5a | CHEMBL3860...)
Affinity DataKi:  16nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11053(reduced monomeric thio of compound 5a | CHEMBL3860...)
Affinity DataKi:  16nMAssay Description:Inhibition of human carbonic anhydrase 2 by stopped flow techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM11053(reduced monomeric thio of compound 5a | CHEMBL3860...)
Affinity DataKi:  79nMAssay Description:Inhibition of human CA5A by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM11053(reduced monomeric thio of compound 5a | CHEMBL3860...)
Affinity DataKi:  114nMAssay Description:Inhibition of human CA5B by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11053(reduced monomeric thio of compound 5a | CHEMBL3860...)
Affinity DataKi:  276nM ΔG°:  -8.85kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11053(reduced monomeric thio of compound 5a | CHEMBL3860...)
Affinity DataKi:  276nMAssay Description:Inhibition of human carbonic anhydrase 1 by stopped flow techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed