BDBM10450 4-Aminoquinoline 7::quinolin-4-amine

SMILES c1ccc2c(c1)c(ccn2)N

InChI Key InChIKey=FQYRLEXKXQRZDH-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 Kd

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 10450   

TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM10450(quinolin-4-amine | 4-Aminoquinoline 7)
Affinity DataIC50: 5.07E+4nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM10450(quinolin-4-amine | 4-Aminoquinoline 7)
Affinity DataIC50: 2.55E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed
TargetNeutrophil cytosol factor 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM10450(quinolin-4-amine | 4-Aminoquinoline 7)
Affinity DataKd:  7.65E+5nMAssay Description:Binding affinity to immobilized recombinant human His-tagged p47phox SH3A-B domain (151 to 285 residues) expressed in Escherichia coli BL21 (DE3) cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNeutrophil cytosol factor 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM10450(quinolin-4-amine | 4-Aminoquinoline 7)
Affinity DataKi:  1.52E+6nMAssay Description:Covalent inhibition of recombinant human His-tagged p47phox SH3A-B domain (151 to 285 residues) expressed in Escherichia coli BL21 (DE3) cells intera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed