BDBM50049251 CHEMBL161318::CHEMBL543888::Pyrrolidin-(2Z)-ylideneamine

SMILES NC1=NCCC1

InChI Key InChIKey=NJBMZYSKLWQXLJ-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50049251   

TargetIndolethylamine N-methyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50049251(CHEMBL161318 | CHEMBL543888 | Pyrrolidin-(2Z)-ylid...)
Affinity DataIC50: 3.36E+4nMAssay Description:Inhibition of New Zealand white rabbit lung INMT using N-methyltryptamine as substrate after 60 to 90 mins by liquid scintillation counting in presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
LigandPNGBDBM50049251(CHEMBL161318 | CHEMBL543888 | Pyrrolidin-(2Z)-ylid...)
Affinity DataIC50: 8.30E+6nMAssay Description:Inhibition of human lung INMT using N-methyltryptamine as substrate after 60 to 90 mins by liquid scintillation counting in presence of S-methyl-[14C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049251(CHEMBL161318 | CHEMBL543888 | Pyrrolidin-(2Z)-ylid...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049251(CHEMBL161318 | CHEMBL543888 | Pyrrolidin-(2Z)-ylid...)
Affinity DataIC50: 9.30E+4nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049251(CHEMBL161318 | CHEMBL543888 | Pyrrolidin-(2Z)-ylid...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibitory activity against human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049251(CHEMBL161318 | CHEMBL543888 | Pyrrolidin-(2Z)-ylid...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of cloned (from RNA) human inducible nitric oxide synthase (hiNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049251(CHEMBL161318 | CHEMBL543888 | Pyrrolidin-(2Z)-ylid...)
Affinity DataIC50: 9.30E+4nMAssay Description:Inhibition of cloned (from RNA) human endothelial constitutive Endothelial nitric oxide synthase (heNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049251(CHEMBL161318 | CHEMBL543888 | Pyrrolidin-(2Z)-ylid...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of cloned (from RNA) human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049251(CHEMBL161318 | CHEMBL543888 | Pyrrolidin-(2Z)-ylid...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibitory activity against Endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049251(CHEMBL161318 | CHEMBL543888 | Pyrrolidin-(2Z)-ylid...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibitory activity against Inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049251(CHEMBL161318 | CHEMBL543888 | Pyrrolidin-(2Z)-ylid...)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibitory activity against Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed