BDBM50216541 CHEMBL613::POA::PYRAZINOIC ACID::PZA::Rifater::pyrazinoicacid

SMILES c1cnc(cn1)C(=O)O

InChI Key InChIKey=NIPZZXUFJPQHNH-UHFFFAOYSA-N

Data  1 IC50  1 EC50

PDB links: 7 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50216541   

TargetNAD-dependent protein deacylase sirtuin-6(Human)
University At Albany

LigandPNGBDBM50216541(CHEMBL613 | Rifater | pyrazinoicacid | PZA | PYRAZ...)
Affinity DataIC50: 9.27E+5nMAssay Description:Inhibitory constants (Ki) and IC50 values were determined under saturating substrate conditions by using a fluorimetric assay (components were purcha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2017
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50216541(CHEMBL613 | Rifater | pyrazinoicacid | PZA | PYRAZ...)
Affinity DataEC50:  6.30E+3nMAssay Description:Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed