BDBM50241553 CHEMBL486986::pomolic acid

SMILES C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2[C@]1(C)O)C(O)=O

InChI Key InChIKey=ZZTYPLSBNNGEIS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50241553   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chosun University

Curated by ChEMBL
LigandPNGBDBM50241553(pomolic acid | CHEMBL486986)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human recombinant PTP1B after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetSentrin-specific protease 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50241553(pomolic acid | CHEMBL486986)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of recombinant human SENP1 assessed as reduction in deSUMOylation using RanGAP1-SUMO1 as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed