BDBM50292477 CHEMBL453568::phyllanthin

SMILES COC[C@H](Cc1ccc(OC)c(OC)c1)[C@H](COC)Cc1ccc(OC)c(OC)c1

InChI Key InChIKey=KFLQGJQSLUYUBF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50292477   

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50292477(phyllanthin | CHEMBL453568)
Affinity DataIC50: 1.00E+6nMAssay Description:Displacement of [125I]endothelin-1 from ETA receptor in rat A10 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50292477(phyllanthin | CHEMBL453568)
Affinity DataIC50: 1.00E+6nMAssay Description:Displacement of [125I]endothelin-1 from human recombinant ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50292477(phyllanthin | CHEMBL453568)
Affinity DataIC50: 5.00E+5nMAssay Description:Displacement of [125I]endothelin-1 from human recombinant ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article