BDBM50102325 6-(4-Methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepine::CHEMBL340801::Perlapine

SMILES CN1CCN(CC1)C1=Nc2ccccc2Cc2ccccc12

InChI Key InChIKey=PWRPUAKXMQAFCJ-UHFFFAOYSA-N

Data  16 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50102325   

TargetD(2) dopamine receptor(Rat)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102325(CHEMBL340801 | Perlapine | 6-(4-Methyl-piperazin-1...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Rat)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50102325(CHEMBL340801 | Perlapine | 6-(4-Methyl-piperazin-1...)
Affinity DataKi:  7.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50102325(CHEMBL340801 | Perlapine | 6-(4-Methyl-piperazin-1...)
Affinity DataKi:  12.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50102325(CHEMBL340801 | Perlapine | 6-(4-Methyl-piperazin-1...)
Affinity DataKi:  12.6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50102325(CHEMBL340801 | Perlapine | 6-(4-Methyl-piperazin-1...)
Affinity DataKi:  13nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50102325(CHEMBL340801 | Perlapine | 6-(4-Methyl-piperazin-1...)
Affinity DataKi:  28nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50102325(CHEMBL340801 | Perlapine | 6-(4-Methyl-piperazin-1...)
Affinity DataKi:  30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50102325(CHEMBL340801 | Perlapine | 6-(4-Methyl-piperazin-1...)
Affinity DataKi:  30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50102325(CHEMBL340801 | Perlapine | 6-(4-Methyl-piperazin-1...)
Affinity DataKi:  30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50102325(CHEMBL340801 | Perlapine | 6-(4-Methyl-piperazin-1...)
Affinity DataKi:  60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50102325(CHEMBL340801 | Perlapine | 6-(4-Methyl-piperazin-1...)
Affinity DataKi:  60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50102325(CHEMBL340801 | Perlapine | 6-(4-Methyl-piperazin-1...)
Affinity DataKi:  70nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50102325(CHEMBL340801 | Perlapine | 6-(4-Methyl-piperazin-1...)
Affinity DataKi:  100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Washington

Curated by PDSP Ki Database
LigandPNGBDBM50102325(CHEMBL340801 | Perlapine | 6-(4-Methyl-piperazin-1...)
Affinity DataKi:  150nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102325(CHEMBL340801 | Perlapine | 6-(4-Methyl-piperazin-1...)
Affinity DataKi:  501nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102325(CHEMBL340801 | Perlapine | 6-(4-Methyl-piperazin-1...)
Affinity DataKi:  501nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
TargetD(3) dopamine receptor(Rat)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM50102325(CHEMBL340801 | Perlapine | 6-(4-Methyl-piperazin-1...)
Affinity DataKi:  919nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2012
Entry Details
PubMed