BDBM50336546 CHEMBL1673415::Palmostatin B

SMILES CCCCCCCCCC[C@H]1[C@H](CCc2ccc(OC)c(OC)c2)OC1=O

InChI Key InChIKey=ASVWFAVGLYUDFD-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50336546   

TargetAcyl-protein thioesterase 1(Human)
Groningen Research Institute of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50336546(Palmostatin B | CHEMBL1673415)
Affinity DataIC50: 670nMAssay Description:Inhibition of APT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 1(Human)
Groningen Research Institute of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50336546(Palmostatin B | CHEMBL1673415)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of APT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50336546(Palmostatin B | CHEMBL1673415)
Affinity DataIC50: 38nMAssay Description:Inhibition of APT2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetPhosphatidylserine lipase ABHD16A(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50336546(Palmostatin B | CHEMBL1673415)
Affinity DataIC50: 99nMAssay Description:Inhibition of human ABHD16A expressed in HEK293 cells preincubated for 30 mins followed by 1-LG substrate addition and measured after 90 to 120 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetPhosphatidylserine lipase ABHD16A(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50336546(Palmostatin B | CHEMBL1673415)
Affinity DataIC50: 100nMAssay Description:Inhibition of ABHD16A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetPhosphatidylserine lipase ABHD16A(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50336546(Palmostatin B | CHEMBL1673415)
Affinity DataIC50: 57nMAssay Description:Reversible inhibition of human ABHD16A expressed in HEK293 cells preincubated for 30 mins followed by 40 fold compound dilution and subsequent 1-LG s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50336546(Palmostatin B | CHEMBL1673415)
Affinity DataKi:  34nMAssay Description:Inhibition of APT2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed